相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia
Claudia Guida et al.
BLOOD (2015)
Disordered signaling governing ferroportin transcription favors breast cancer growth
Yue Chen et al.
CELLULAR SIGNALLING (2015)
A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis
Patrick Gutschow et al.
HAEMATOLOGICA (2015)
The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study
Antonio Maccio et al.
HAEMATOLOGICA (2015)
Hepcidin-dependent and hepcidin-independent regulation of erythropoiesis in a mouse model of anemia of chronic inflammation
Jacqueline M. Langdon et al.
AMERICAN JOURNAL OF HEMATOLOGY (2014)
A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin
Airie Kim et al.
BLOOD (2014)
Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus
Sara Gardenghi et al.
BLOOD (2014)
Erythroferrone contributes to recovery from anemia of inflammation
Leon Kautz et al.
BLOOD (2014)
The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6
Claire Mayeur et al.
BLOOD (2014)
HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression
Xing-gang Wu et al.
BLOOD (2014)
Unexplained anaemia in the elderly is characterised by features of low grade inflammation
Andrew S. Artz et al.
BRITISH JOURNAL OF HAEMATOLOGY (2014)
Disordered hepcidin-ferroportin signaling promotes breast cancer growth
Shuping Zhang et al.
CELLULAR SIGNALLING (2014)
Hepcidin Induction by Pathogens and Pathogen-Derived Molecules Is Strongly Dependent on Interleukin-6
Richard Rodriguez et al.
INFECTION AND IMMUNITY (2014)
Identification of erythroferrone as an erythroid regulator of iron metabolism
Leon Kautz et al.
NATURE GENETICS (2014)
Mouse Models of Anemia of Cancer
Airie Kim et al.
PLOS ONE (2014)
Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections
Andrew E. Armitage et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Iron, anemia and hepcidin in malaria
Natasha Spottiswoode et al.
FRONTIERS IN PHARMACOLOGY (2014)
An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe-/- mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia
Paul J. Schmidt et al.
BLOOD (2013)
Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age
Bryan J. McCranor et al.
HAEMATOLOGICA (2013)
Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice
Shuling Guo et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Role of Hepcidin in the Setting of Hypoferremia during Acute Inflammation
Jean-Christophe Deschemin et al.
PLOS ONE (2013)
Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2
Paul J. Schmidt et al.
AMERICAN JOURNAL OF HEMATOLOGY (2012)
Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis
Emilio Ramos et al.
BLOOD (2012)
Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling
Celine Besson-Fournier et al.
BLOOD (2012)
Pegylated interferon-α induced hypoferremia is associated with the immediate response to treatment in hepatitis C
John D. Ryan et al.
HEPATOLOGY (2012)
Sustained Submicromolar H2O2 Levels Induce Hepcidin via Signal Transducer and Activator of Transcription 3 (STAT3)
Gunda Millonig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation
Flavia D'Alessio et al.
JOURNAL OF HEPATOLOGY (2012)
Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis
Wenjie Chen et al.
BLOOD (2011)
Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2
Daniel F. Wallace et al.
BLOOD (2011)
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats
Igor Theurl et al.
BLOOD (2011)
Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice
Andrea U. Steinbicker et al.
BLOOD (2011)
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation
Andrea U. Steinbicker et al.
BLOOD (2011)
Hepcidin regulation by innate immune and infectious stimuli
Andrew E. Armitage et al.
BLOOD (2011)
Conditional Disruption of Mouse Hfe2 Gene: Maintenance of Systemic Iron Homeostasis Requires Hepatic but Not Skeletal Muscle Hemojuvelin
Konstantinos Gkouvatsos et al.
HEPATOLOGY (2011)
Investigation of a Researcher's Death Due to Septicemic Plague
Karen M. Frank et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
High-Throughput Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry Method for Quantification of Hepcidin in Human Urine
Damon S. Anderson et al.
ANALYTICAL CHEMISTRY (2010)
Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia
Barbra J. Sasu et al.
BLOOD (2010)
In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2
Ken Maes et al.
BLOOD (2010)
STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo
Ryotaro Sakamori et al.
JOURNAL OF GASTROENTEROLOGY (2010)
Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness
Jaroslav Truksa et al.
BLOOD (2009)
Combined Deletion of Hfe and Transferrin Receptor 2 in Mice Leads to Marked Dysregulation of Hepcidin and Iron Overload
Daniel F. Wallace et al.
HEPATOLOGY (2009)
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
Delphine Meynard et al.
NATURE GENETICS (2009)
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
Billy Andriopoulos et al.
NATURE GENETICS (2009)
ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity
Susana J. Oliveira et al.
PLOS ONE (2009)
ER Stress Controls Iron Metabolism Through Induction of Hepcidin
Chiara Vecchi et al.
SCIENCE (2009)
Secretion of bioactive hepcidin-25 by liver cells correlates with its gene transcription and points towards synergism between iron and inflammation signaling pathways
Apriliana E. R. Kartikasari et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2008)
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
Yin Xia et al.
BLOOD (2008)
The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression
Paul J. Schmidt et al.
CELL METABOLISM (2008)
Involvement of hepcidin in the anemia of multiple myeloma
Sanjai Sharma et al.
CLINICAL CANCER RESEARCH (2008)
A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells
Maria Vittoria Verga Falzacappa et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2008)
Autocrine formation of hepcidin induces iron retention in human monocytes
Igor Theurl et al.
BLOOD (2008)
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Paul B. Yui et al.
NATURE CHEMICAL BIOLOGY (2008)
Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation
Cindy N. Roy et al.
BLOOD (2007)
STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo
Antonello Pietrangelo et al.
GASTROENTEROLOGY (2007)
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation
Maria Vittoria Verga Falzacappa et al.
BLOOD (2007)
Interleukin induces hepcidin expression through STAT3
Diedra M. Wrighting et al.
BLOOD (2006)
Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis
Jeanne-Claire Lesbordes-Brion et al.
BLOOD (2006)
TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens
C Peyssonnaux et al.
BLOOD (2006)
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
JL Babitt et al.
NATURE GENETICS (2006)
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
KZ Zhang et al.
CELL (2006)
A role of SMAD4 in iron metabolism through the positive regulation of hepicidin expression
RH Wang et al.
CELL METABOLISM (2005)
Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs
S Rivera et al.
BLOOD (2005)
Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS
E Kemna et al.
BLOOD (2005)
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
V Niederkofler et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
A mouse model of juvenile hemochromatosis
FW Huang et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin
H Drakesmith et al.
BLOOD (2005)
Medical progress: Anemia of chronic disease
G Weiss et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Regulation of hepcidin transcription by interleukin-1 and interleukin-6
P Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis
H Kawabata et al.
BLOOD (2005)
Simultaneous analysis of host and pathogen interactions during an in vivo infection reveals local induction of host acute phase response proteins, a novel bacterial stress response, and evidence of a host-imposed metal ion limited environment
ST Motley et al.
CELLULAR MICROBIOLOGY (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
G Papanikolaou et al.
NATURE GENETICS (2004)
Decreased hepcidin mRNA expression in thalassemic mice
K Adamsky et al.
BRITISH JOURNAL OF HAEMATOLOGY (2004)
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice
CN Roy et al.
NATURE GENETICS (2004)
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
E Nemeth et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis
M Muckenthaler et al.
NATURE GENETICS (2003)
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
E Nemeth et al.
BLOOD (2003)
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease
DA Weinstein et al.
BLOOD (2002)
Decreased liver hepcidin expression in the Hfe knockout mouse
KA Ahmad et al.
BLOOD CELLS MOLECULES AND DISEASES (2002)
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
G Nicolas et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
G Nicolas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge
H Shike et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites
AP West et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
G Nicolas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
CH Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
C Pigeon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
S Abboud et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
C Camaschella et al.
NATURE GENETICS (2000)
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
A Donovan et al.
NATURE (2000)
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
AT McKie et al.
MOLECULAR CELL (2000)
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
A Krause et al.
FEBS LETTERS (2000)
分享论文
