期刊
CURRENT OPINION IN CELL BIOLOGY
卷 13, 期 3, 页码 332-337出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(00)00216-7
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Loss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects.
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