4.4 Article

Plasmodium falciparum homologue of the genes for Plasmodium vivax and Plasmodium yoelii adhesive proteins, which is transcribed but not translated

期刊

INFECTION AND IMMUNITY
卷 69, 期 6, 页码 3635-3645

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AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.69.6.3635-3645.2001

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  1. Medical Research Council [MC_U117532067] Funding Source: researchfish
  2. Medical Research Council [MC_U117532067] Funding Source: Medline
  3. MRC [MC_U117532067] Funding Source: UKRI

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The 235-kDa family of rhoptry proteins in Plasmodium yoelii and the two reticulocyte binding proteins of P. vivax comprise a family of proteins involved in host cell selection and erythrocyte invasion. Here we described a member of the gene family found in P. falciparum (PfRH3) that is transcribed in its entirety, under stage-specific control, with correct splicing of the intron, but appears not to be translated, probably due to two reading frameshifts at the 5' end of the gene.

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