期刊
JOURNAL OF CLINICAL EPIDEMIOLOGY
卷 54, 期 6, 页码 587-596出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S0895-4356(00)00372-3
关键词
health-related quality of life; chronic liver disease; questionnaires; methodology
Four generic [the Sickness Impact Profile (SIP-68), Short-Form Health Survey (SF-36), EuroQol instrument (EQ-5D), COOP/ WONCA charts], two domain-specific health-related quality of life measures [the sexuality scale of the HIV Overview Problems Evaluating System (HOPES), Multi-dimensional Fatigue Index (MFI-20)], and a self-developed 12-item symptom index were compared in terms of feasibility, test-retest reliability, internal consistency reliability, construct validity, and known groups validity in patients with chronic liver disease. All instruments could be completed within 10 min and exhibited a good psychometric performance in patients with chronic liver disease. The SF-36 and the MFI-20 performed relatively best in terms of reliability, construct validity, and discriminative ability. The sexuality scale of the HOPES demonstrated a relatively poor performance, as the missing value rate was higher than 5%. Further research is needed into the sensitivity to important clinical changes of the instruments. (C) 2001 Elsevier Science Inc. All rights reserved.
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