期刊
PLANTA MEDICA
卷 67, 期 4, 页码 322-325出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2001-14337
关键词
Lonicera bournei Hemsl; Caprifoliaceae; quinic acid derivatives; caffeic acid derivatives; D-galactosamine (D-GalN); tumor necrosis factor alpha (TNF-alpha); hepatoprotective activity
13 quinic acid derivatives along with caffeic acid, methyl caffeate, myo-inositol, bis[5-formylfurfuryl] ether and 6,7-dihydroxycoumarin were isolated from the ethanol extract of the flower buds of Lonicero bournei Hemsl., among which 8 compounds were firstly obtained from this genus. The effects of different solvent soluble fractions of the ethanol extract and the pure compounds on heptocyte death induced by D-galactosamine (D-GalN)ltumor necrosis factor alpha (TNF-alpha) were studied, and the structure-activity relationships were also discussed.
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