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The physics of molecular motors

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ACCOUNTS OF CHEMICAL RESEARCH
卷 34, 期 6, 页码 412-420

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AMER CHEMICAL SOC
DOI: 10.1021/ar0001719

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  1. NIGMS NIH HHS [R01 GM63808, R01 GM59875-01A1, GM-32543] Funding Source: Medline

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Molecular motors convert chemical energy into mechanical force and movement. Operating at energies just above those of the thermal bath, these motors experience large fluctuations, and their physical description must be necessarily stochastic. Here, motor operation is described as a biased diffusion on a potential energy surface defined by the interactions of the motor with its track and its fuel. These ideas are illustrated with a model of the rotary movement of the F-o motor.

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