Cytochrome P-450 model reactions: a kinetic study of epoxidation of alkenes by iron phthalocyanine

A kinetic study for measuring the relative rate of the catalytic epoxidation of various alkenes has been employed based upon the disappearance of the 1,4-diphenylbutadiene. Iron(III) phthalocyanine chloride as catalyst, imidazole as cocatalyst, iodosylbenzene as oxygen donor and a mixture of dichloromethane, methanol, water (80:18:2) as solvent, were used for achieving to a homogeneous system. Effects of nitrogen donor bases such as pyridine, piperidine and collidine on the yield of alkenes epoxidation were investigated and possibility of the same mechanism for iron phthalocyanine and porphyrin has been demonstrated. (C) 2001 Elsevier Science B.V. All rights reserved.