Why do birds sleep with one eye open? Light exposure of the chick embryo as a determinant of monocular sleep

Together with some aquatic mammals, birds exhibit a unique behavioral and electrophysiological state called unihemispheric sleep, in which one cerebral hemisphere is awake and the other is sleeping [1], Slow-wave sleep in one hemisphere is associated with closure of the contralateral eye, while the eye contralateral to the awake hemisphere is open; closure of both eyes, in contrast, is associated with bihemispheric slow-wave sleep or with REM sleep [1-3]. During the last few days of incubation, the chick's embryo is turned in the egg so that it occludes its left eye, whereas light entering through the shell can stimulate the right eye [4], Here we show that in the first two days after hatching, chicks coming from eggs incubated in the light prevalently slept with their right eye open, whereas those coming from eggs incubated in the dark prevalently slept with their left eye open. Thus, asymmetric light stimulation in the embryo can modulate the left-right direction of eye opening during post-hatching monocular sleep. (C) 2001 Elsevier Science Ltd. All rights reserved.