期刊
BULLETIN OF MATHEMATICAL BIOLOGY
卷 63, 期 4, 页码 715-730出版社
SPRINGER
DOI: 10.1006/bulm.2001.0244
关键词
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We study the evolution of large but finite asexual populations evolving in fitness landscapes in which all mutations are either neutral or strongly deleterious. We demonstrate that despite the absence of higher fitness genotypes, adaptation takes place as regions with more advantageous distributions of neutral genotypes are discovered. Since these discoveries are typically rare events, the population dynamics can be subdivided into separate epochs, with rapid transitions between them. Within one epoch, the average fitness in the population is approximately constant. The transitions between epochs, however, are generally accompanied by a significant increase in the average fitness. We verify our theoretical considerations with two analytically tractable bitstring models. (C) 2001 Society for Mathematical Biology.
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