期刊
NEUROREPORT
卷 12, 期 9, 页码 1879-1884出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200107030-00023
关键词
cerebellum; forward model; internal model; PET; prediction; sensorimotor control
We used (H2O)-O-15 PET to examine neural responses to parametrically varied degrees of discrepancy between the predicted and actual sensory consequences of movement. Subjects used their right hand to move a robotic arm. The motion of this robotic arm determined the position of a second foam-tipped robotic arm, which made contact with the subject's left palm. Using this robotic interface, computer controlled delays were introduced between the movement of the right hand and the tactile stimulation on the left. Activity in the right lateral cerebellar cortex showed a positive correlation with delay. These results suggest the cerebellum is involved in signalling the sensory discrepancy between the predicted and actual sensory consequences of movements. NeuroReport 12:1879-1884 (C) 2001 Lippincott Williams & Wilkins.
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