期刊
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
卷 27, 期 3, 页码 319-328出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.berh.2013.07.004
关键词
Lupus nephritis; Treatment; Immunosuppression; Optimal care
类别
Despite decades of clinical research aimed at finding the most appropriate immunosuppressive regime, lupus nephritis (LN) remains one of the major disease manifestations of systemic lupus erythematosus (SLE) with a great impact on survival and quality of life. We start this review by defining the disease burden, the real-world challenges and the poor prognostic factors. We then discuss the current anti-inflammatory, cytotoxic and biologic therapies, with special emphasis on the need for optimal global care. (C) 2013 Elsevier Ltd. All rights reserved.
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