期刊
MAGNETIC RESONANCE IN MEDICINE
卷 46, 期 2, 页码 395-400出版社
JOHN WILEY & SONS INC
DOI: 10.1002/mrm.1203
关键词
MR spectroscopy; quantification; motion; physiologic fluctuation; artifact correction
A postprocessing method to restore motion-related signal loss and line-shape deterioration in single-volume proton MR spectroscopy (MRS) is presented. Each acquisition is corrected by its phase offset and frequency shift, extracted from the residual water signal prior to averaging. Requirements are good gradient selection and selective suppression of CSF in residual water. Stimulated echo acquisition mode (STEAM) spectra (TE = 30 ms) were analyzed using the LCModel program to study gains in metabolite signal and spectral quality in five brain regions. Increases of total N-acetyl-aspartate concentrations of up to 5% were observed. The method may be beneficial for clinical examinations of less compliant subjects and for dynamic spectroscopy. (C) 2001 Wiley-Liss, Inc.
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