期刊
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
卷 26, 期 4, 页码 495-501出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.bpobgyn.2012.02.004
关键词
microbicides; implementation; low income countries; HIV prevention
资金
- Center for the AIDS Program of Research in South Africa (CAPRISA) [NIH/NIAID U01AI068619, CAPRISA 004]
- United States Agency for International Development (USAID)
- FHI [GPO-A-00-05-00022-00, 132119]
- LIFElab, a biotechnology center of the South African Department of Science and Technology
- Columbia University-Southern African Fogarty AIDS International Training and Research Programme (AITRP) [D43TW00231]
The magnitude of the global human immunodeficiency virus (HIV) epidemic is determined by women from lower income countries, specifically sub-Saharan Africa. Microbicides offer women who are unable to negotiate safe sex practices a self-initiated HIV prevention method. Of note, is its potential to yield significant public health benefits even with relatively conservative efficacy, coverage and user adherence estimates, making microbicides an effective intervention to invest scarce healthcare resources. Existing healthcare delivery systems provide an excellent opportunity to identify women at highest risk for infection and to also provide an access point to initiate microbicide use. Innovative quality improvement approaches, which strengthen existing sexual reproductive health services and include HIV testing, and linkages to care and treatment services, provide an opportunity to lay the foundations for wide-scale provision of microbicides. The potential to enhance health outcomes in women and infants and potentially affect rates of new HIV infection may soon be realised. (C) 2012 Elsevier Ltd. All rights reserved.
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