期刊
BIOSCIENCE REPORTS
卷 21, 期 4, 页码 407-418出版社
PORTLAND PRESS LTD
DOI: 10.1023/A:1017987608937
关键词
ocular; tear film; lipid; polar; surfactant; disease
The outer layer of the tear him the lipid layer has numerous functions. It is a composite monolayer composed of a polar phase with surfactant properties and a nonpolar phase. In order to achieve an effective lipid layer, the nonpolar phase, which retards skater vapor transmission, is dependent on a properly structured polar phase. Additionally. this composite lipid layer must maintain its integrity during a blink. The phases of the lipid layer depend on both lipid tape as well as fatty acid and alcohol composition for functionality. Surprisingly, the importance of the composition of the aqueous layer of the tear film in proper structuring of the lipid layer has not been recognized. Finally, lipid layer abnormalities and their relationship to ocular disease are beginning to be clarified.
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