期刊
LARYNGOSCOPE
卷 111, 期 8, 页码 1313-1317出版社
WILEY
DOI: 10.1097/00005537-200108000-00001
关键词
laryngopharyngeal reflux; LPR; extraesophageal reflux; proton pump inhibitors; treatment outcomes; reflux finding score
Background: The evaluation of medical and surgical outcomes relies on methods of accurately quantifying treatment results. Currently, there is no validated instrument whose purpose is to document the physical findings and severity of laryngopharyngeal reflux (LPR). Objective. To evaluate the validity and reliability of the reflux finding score (RFS). Methods: Forty patients with LPR confirmed by double-probe pH monitoring were evaluated pretreatment and 2,4, and 6 months after treatment. The RFS was documented for each patient at each visit. For test-retest intraobserver reliability assessment, a blinded laryngologist determined the RFS on two separate occasions. To evaluate interobserver reliability, the RIPS was determined by two different blinded laryngologists. Results. The mean age of the cohort was 50 years (+/- 12 standard deviation [SDI). Seventy-three percent were women. The RFS at entry was 11.5 (+/- 5.2 SD). This score improved to 9.3 (+/- 4.7 SD) at 2 months, 7.3 (+/- 5.5 SD) at 4 months, and 6.1 (+/- 5.2 SD) at 6 months of treatment (P < .001 with trend). The mean RFS for laryngologist no. 1 was 10.8 (+/- 4.1 SD) at the initial screening and 10.8 (+/- 4.0 SD) at the repeat evaluation (r = 0.95, P < .001). The mean RFS for laryngologist no. 2 was 11.1 (+/- 3.8 SD) at the initial screening and 10.9 (+/- 3.7 SD) at the repeat evaluation (r = 0.95, P < .001). The correlation coefficient for interobserver variability was 0.90 (P < .001). Conclusions. The RIPS accurately documents treatment efficacy in patients with LPR It demonstrates excellent inter- and intraobserver reproducibility.
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