期刊
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
卷 25, 期 5, 页码 813-824出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.beem.2011.05.004
关键词
stress hyperglycemia; inpatient hyperglycemia; hospital hyperglycemia; ICU
资金
- American Diabetes Association [7-07-CR-56]
- NIH/NCRR [M01 RR-00039]
- Sanofi-Aventis
- Merck
- Glaxo Pharmaceuticals
- National Institute of Health [K08 DK0830361]
Hyperglycemia is a common and costly health care problem in hospitalized patients. In hospital hyperglycemia is defined as any glucose value >7.8 mmol/l (140 mg/dl). Hyperglycemia is present in 40% of critically ill patients and in up to 80% of patients after cardiac surgery, with similar to 80% of ICU patients with hyperglycemia having no history of diabetes prior to admission. The risk of hospital complications relates to the severity of hyperglycemia, with a higher risk observed in patients without a history of diabetes compared to those with known diabetes. Improvement in glycemic control reduces hospital complications and mortality; however, the ideal glycemic target has not been determined. A target glucose level between 7.8 and 10.0 mmol/l (140 and 180 mg/dl) is recommended for the majority of ICU patients. This review aims to present updated recommendations for the inpatient management of hyperglycemia in critically ill patients with and without a history of diabetes. (C) 2011 Elsevier Ltd. All rights reserved.
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