期刊
FASEB JOURNAL
卷 15, 期 10, 页码 1671-1676出版社
FEDERATION AMER SOC EXP BIOL
DOI: 10.1096/fj.01-0024lsf
关键词
cholesterol; research funding; statins; HMG CoA reductase; mevastatin
'Blockbuster' drugs, which are widely prescribed and improve the health of millions, often originate in fundamental laboratory research. An important example of such drugs are the cholesterol-lowering drugs called 'statins', including Zocor, Pravachol, and Lipitor, which millions of people take in the U.S. every year. This short paper outlines the direct and indirect contributions of federally sponsored research to the development of these important drugs.
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