4.5 Article

Aminofluorination of 2-alkynylanilines: a Au-catalyzed entry to fluorinated indoles

期刊

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷 10, 期 -, 页码 449-458

出版社

BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.10.42

关键词

2-alkynylanilines; fluorination; gold catalysis; indoles; tandem reactions

资金

  1. Universita dell'Aquila
  2. Ministsre de l'Education et de la Recherche
  3. Centre National de la Recherche Scientifique (CNRS)

向作者/读者索取更多资源

The scope and limitations of gold-catalyzed tandem cycloisomerization/fluorination reactions of unprotected 2-alkynylanilines to have access to 3,3-difluoro-2-aryl-3H-indoles and 3-fluoro-2-arylindoles are described. An unprecedented aminoauration/oxidation/ fluorination cascade reaction of 2-alkynylanilines bearing a linear alkyl group on the terminal triple bond is reported.

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