Visible-light photoredox catalyzed synthesis of pyrroloisoquinolines via organocatalytic oxidation/[3+2] cycloaddition/oxidative aromatization reaction cascade with Rose Bengal

Pyrrolo[2,1-a] isoquinoline alkaloids have been prepared via a visible light photoredox catalyzed oxidation/[3 + 2] cycloaddition/oxidative aromatization cascade using Rose Bengal as an organo-photocatalyst. A variety of pyrroloisoquinolines have been obtained in good yields under mild and metal-free reaction conditions.