期刊
MECHANISMS OF DEVELOPMENT
卷 106, 期 1-2, 页码 175-180出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0925-4773(01)00430-0
关键词
roundabout; Robo1; Robo2; Rig1; Slit1; Slit2; Slit3; chick; mouse; limb development; muscle; innervation; axon guidance; chrondrogenesis; gene expression; apical ectodermal ridge; mesenchyme
We report the cloning and expression during limb development of the chicken Slit1, Slit2, and Slit3 ligands, and Robo1 and Robo2 receptor genes. We also compare the expression patterns of Robo1 and Robo2 in developing chick and mouse hindlimbs. These genes are expressed in regions of muscle development, chrondrogenesis, and axon guidance. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
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