期刊
AMERICAN JOURNAL OF EPIDEMIOLOGY
卷 154, 期 3, 页码 230-235出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/aje/154.3.230
关键词
coronary disease; prospective studies; stress; survival analysis
资金
- NHLBI NIH HHS [N01-HC-55022, 5-T32-HL07055, N01-HC-55015, N01-HC-55016, N01-HC-55020, N01-HC-55019, N01-HC-55018] Funding Source: Medline
The objective of the study was to determine which component of an anger-prone personality more strongly predicts coronary heart disease (CHD) risk. Proneness to anger, as assessed by the Spielberger Trait Anger Scale, is composed of two distinct subcomponents-anger-temperament and anger-reaction. Participants were 12,990 middle-aged Black men and women and White men and women from the Atherosclerosis Risk in Communities Study who were followed for the occurrence of acute myocardial infarction (Ml)/fatal CHID, silent MI, or cardiac revascularization procedures (average = 53 months; maximum = 72 months) through December 31, 1995. Among normotensive persons, a strong, angry temperament (tendency toward quick, minimally provoked, or unprovoked anger) was associated with combined CHID (acute MI/fatal CHID, silent Ml, or cardiac revascularization procedures) (multivariate-adjusted hazard ratio = 2.10, 95% confidence interval: 1.34, 3.29) and with hard events (acute MI/fatal CHD) (multivariate adjusted hazard ratio = 2.28, 95% confidence interval: 1.29, 4.02). CHID event-free survival among normotensives who had a strong, angry temperament was not significantly different from that of hypertensives at either level of anger. These data suggest that a strong, angry temperament rather than anger in reaction to criticism, frustration, or unfair treatment places normotensive, middle-aged persons at increased risk for cardiac events and may confer a CHD risk similar to that of hypertension.
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