期刊
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷 9, 期 -, 页码 64-73出版社
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.9.8
关键词
caged compounds; cell signaling; electrophysiology; neuronal currents; photolabile neurotransmitters; rates of reaction; receptor antagonism
资金
- NIH [GM53395, NS69720]
Caged compounds are small organic molecules that can be photoactivated with brief pulses of light. They are widely used to study a great variety of biological processes by physiologists, cell biologists and neuroscientists. Initially made and invented by biologists in the late 1970s, they are now made mostly by chemists, often without any dialogue with the end users, the biologists. The idea for this review is to stimulate interaction between the two communities to further the creative development and application of these powerful optical probes.
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