期刊
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷 9, 期 -, 页码 254-259出版社
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.9.30
关键词
coumarin; fluorescent probe; halogen derivatives; non-natural amino acid; Pechmann condensation
资金
- National Science Foundation of China [21102172, 90913022]
- Major State Basic Research Program of China [2010CB912301, 2009CB825505]
- Scientific Research Foundation for the Returned Overseas Chinese Scholars
- State Education Ministry
- Fundamental Research Funds for the Central Universities (Wuhan University of Technology) [133114001]
- Wuhan University of Technology
The hydrochloride of the racemic amino acid (2-(7-hydroxycoumarin-4-yl) ethyl)glycine, which can serve as a fluorescent probe in proteins, and two halogen derivatives of it, were synthesized by using a new synthetic protocol in five steps. It is less costly and relatively easy to prepare this kind of fluorescent amino acid with the new synthetic method. Furthermore, it can be applied to synthesize other derivatives of the coumarin amino acid with some specific properties.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
