期刊
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷 7, 期 -, 页码 179-197出版社
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.7.25
关键词
alkylidenemalononitriles; 5-aminopyrazoles; hydrazines; beta-ketonitriles; malononitriles
资金
- Council of Scientific and Industrial Research, New Delhi
The biological and medicinal properties of 5-aminopyrazoles have prompted enormous research aimed at developing synthetic routes to these heterocyles. This review focuses on the biological properties associated with this system. Various synthetic methods developed up to 2010 for these compounds are described, particularly those that involve the reactions of beta-ketonitriles, malononitrile, alkylidenemalononitriles and their derivatives with hydrazines, as well as some novel miscellaneous methods.
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