期刊
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷 6, 期 -, 页码 -出版社
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.6.65
关键词
asymmetric synthesis; electrophilic; fluorine; reagent; trifluoromethylation
资金
- JSPS in Japan
- CNRS in France
- JSPS [21390030]
- Grants-in-Aid for Scientific Research [21390030] Funding Source: KAKEN
Since the discovery by Yagupolskii and co-workers that S-trifluoromethyl diarylsulfonium salts are effective for the trifluoromethylation of thiophenolates, the design and synthesis of electrophilic trifluoromethylating reagents have been extensively researched in both academia and industry, due to the significant unique features that trifluoromethylated compounds have in pharmaceuticals, agricultural chemicals, and functional materials. Several effective reagents have been developed by the groups of Yagupolskii, Umemoto, Shreeve, Adachi, Magnier, Togni and Shibata. Due to the high stability and reactivity of these reagents, a series of Umemoto reagents, Togni reagent and Shibata reagent are now commercially available. In this review, we wish to briefly provide a historical perspective of the development of so-called shelf-stable electrophilic trifluoromethylating reagents, although this field is in constant development.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据