Development of p-phenylbenzyl as a new protecting group:: protection and deprotection of alcohols

p-Phenylbenzyl is developed as a new 'PMB' like protecting group. p-Phenylbenzyl (PPB) ethers were prepared from alcohols with PPBBr-NaH or p-phenylbenzyl trichloroacetimidate-TfOH and subjected to oxidative deprotection using DDQ or DDQ (10 mol%)-3 equiv, Mn(OAC)(3). (C) 2001 Elsevier Science Ltd. All rights reserved.