期刊
ORGANIC LETTERS
卷 3, 期 16, 页码 2509-2511出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol016169e
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资金
- NIGMS NIH HHS [GM 52190] Funding Source: Medline
[GRAPHICS] Highly charged peptides ranging In length from 17 to 33 residues have been efficiently tricoupled to a trialkyne nucleus by using a Sonogashira Pd(0) coupling strategy under both acidic (pH 5.0) and basic (pH 7.5) conditions. These results demonstrate the utility of Pd(0) to construct protein-sized structures (12,000 mol wt) in aqueous milieu.
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