期刊
TETRAHEDRON-ASYMMETRY
卷 12, 期 15, 页码 2147-2152出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0957-4166(01)00384-6
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A series of binaphthyl-derived amino alcohols were synthesized and used as catalytic ligands in the asymmetric alkynylation of aromatic aldehydes in the presence of a dialkylzinc reagent. The alkynylation of a variety of aromatic aldehydes gave the corresponding chiral propargylic alcohols in 61-93% e.e. (C) 2001 Published by Elsevier Science Ltd.
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