期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 67, 期 9, 页码 4358-4360出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.67.9.4358-4360.2001
关键词
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The filamentous fungus Cunninghamella elegans ATCC 36112 metabolized the triphenylmethane dye malachite green with a first-order rate constant of 0.029 mu mol h(-1) (mg of cells)(-1). Malachite green was enzymatically reduced to leucomalachite green and also converted to N-demethylated and N-oxidized metabolites, including primary and secondary arylamines. Inhibition studies suggested that the cytochrome P450 system mediated both the reduction and the N-demethylation reactions.
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