期刊
BEHAVIOURAL BRAIN RESEARCH
卷 238, 期 -, 页码 200-205出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbr.2012.10.031
关键词
Fear conditioning; Place avoidance; Extinction; Renewal; Empathy; Anxiety disorders
资金
- Polish Ministry of Science and Higher Education [COST Action BM0901]
- Switzerland through the Swiss Contribution to the enlarged European Union
- Foundation for Polish Science through its program HOMING
Return of fear after extinction is a considerable challenge for the efficacy of exposure-based therapies. Fear recovery is most often modeled in the laboratory by changing the experimental context and studied in isolated animals. Since social context is an important factor affecting behavior, the question arises how it influences the recovery of extinguished fear. Here we present two novel behavioral models that allow studying social modulation of extinction memory retrieval. We show that the presence of a fearful cage mate results in a robust renewal of freezing as well as avoidance responses that were previously successfully extinguished. (c) 2012 Elsevier B.V. All rights reserved.
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