期刊
BEHAVIOURAL BRAIN RESEARCH
卷 208, 期 1, 页码 243-249出版社
ELSEVIER
DOI: 10.1016/j.bbr.2009.12.001
关键词
Orbitofrontal cortex; Social transmission of food preference; Hippocampus; Systems consolidation
资金
- National Science Foundation [IBN-0849800]
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [0849800] Funding Source: National Science Foundation
A role for prefrontal cortex has been proposed in systems consolidation of memory. The current study examined the effects of excitotoxic lesions of the orbitofrontal cortex (OFC) in rats on acquisition and remote recall of socially transmitted food preferences (STFP). Subjects received excitotoxic lesions of the OFC, and they were trained on two food preferences. They were tested I h after the first training session to determine the effect of the lesion on acquisition. The following day, they were trained on a second preference and tested 10 days later to determine the effect of the lesion on remote recall. OFC lesions did not impair either STFP acquisition OF remote recall in comparisons with sham-operated animals. In addition, a subset of animals underwent odor discrimination and reversal training. Consistent with previous reports, subjects with OFC lesions required more trials to reach criterion and made more errors during reversal training than did sham-operated animals. Taken together, the results of the present study indicate that the orbitofrontal cortex is not necessary for acquisition or systems consolidation of socially transmitted food preferences. (C) 2009 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据