期刊
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
卷 281, 期 3, 页码 R971-R978出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/ajpregu.2001.281.3.R971
关键词
palatability; sodium; taste; electrophysiology; nucleus tractus solitarii
类别
资金
- NIDDK NIH HHS [DK-46791] Funding Source: Medline
Calcium-deprived rats develop a compensatory appetite for substances that contain calcium. To investigate the role of gustatory factors in calcium appetite, we recorded the extracellular activity of single neurons in the nucleus of the solitary tract of calcium-deprived and replete rats. The activity evoked by a broad array of taste stimuli was examined in 51 neurons from replete rats and 47 neurons from calcium-deprived rats. There were no differences between the groups in the responses of all neurons combined. However, neurons with sugar-oriented response profiles gave significantly larger responses to 3, 10, and 100 mM CaCl2 in the calcium-deprived group than did corresponding cells in the replete group. This difference in taste-evoked responding may underlie an increase in the palatability of CaCl2 and, in turn, contribute to the expression of calcium appetite.
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