期刊
BEHAVIOURAL BRAIN RESEARCH
卷 189, 期 2, 页码 284-297出版社
ELSEVIER
DOI: 10.1016/j.bbr.2008.01.005
关键词
conditioned disgust; taste avoidance; taste reactivity; lithium; illness; nausea; fear; neurotoxin; lesion; amygdala
When rats are intraorally exposed to saccharin solution that has previously been paired with lithium chloride (LiCl), they display Pavlovian conditioned disgust reactions. When exposed to LiCl-paired saccharin solution by bottle, they display suppressed instrumental approach to the bottle resulting in suppressed consumption. The present experiments demonstrated that while neither neurotoxin-induced lesions of the basolateral amygdala (BLA) nor the central nucleus of the amygdala (CeA) attenuated the display of Pavlovian conditioned disgust reactions, lesions of the BLA (but not the CeA) attenuated instrumental conditioned avoidance of the taste. The results are discussed in light of current models of the role of the amygdala in aversive learning. (C) 2008 Elsevier B.V. All rights reserved.
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