期刊
BEHAVIORAL NEUROSCIENCE
卷 124, 期 1, 页码 26-43出版社
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/a0018464
关键词
nucleus accumbens; impulsivity; delay discounting; timing; rats
资金
- Biotechnology and Biological Sciences Research Foundation [BB/EO08224/1]
- BBSRC [BB/E008224/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/E008224/1] Funding Source: researchfish
The present series of experiments aimed to pinpoint the source of nucleus accumbens core (AcbC) effects on delay discounting. Rats were trained with an impulsive choice procedure between an adjusting smaller sooner reward and a fixed larger later reward. The AcbC-lesioned rats produced appropriate choice behavior when the reward magnitude was equal. An increase in reward magnitude resulted in a failure to increase preference for the larger later reward in the AcbC-lesioned rats, whereas a decrease in the larger later reward duration resulted in normal alterations in choice behavior in AcbC-lesioned rats. Subsequent experiments with a peak timing (Experiments 2 and 3) and a behavioral contrast (Experiment 4) indicated that the AcbC-lesioned rats suffered from decreased incentive motivation during changes in reward magnitude (Experiments 2 and 4) and when expected rewards were omitted (Experiments 2 and 3), but displayed intact anticipatory timing of reward delays (Experiments 2 and 3). The results indicate that the nucleus accumbens core is critical for determining the incentive value of rewards, but does not participate in the timing of reward delays.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据