期刊
TETRAHEDRON LETTERS
卷 42, 期 39, 页码 6941-6942出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(01)01412-5
关键词
chemo and regioselective; oxidative nuclear bromination; lithium bromide; ceric ammonium nitrate
A mild, efficient and highly chemo- and regioselective method for the bromination of electron rich aromatic molecules has been developed by electrophilic substitution of Br+, which was generated in situ from LiBr using ceric ammonium nitrate as the oxidant. Free aromatic amines remained unaffected under the reaction conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.
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