Expression systems for use in actinomycetes and related organisms

There have been significant advances in genetic and molecular approaches to understanding the physiology of organisms belonging to the genera Mycobacterium, Corynebacterium, Nocardia and Streptomyces. This review discusses recent advances in heterologous protein expression in members of the actinomycete group, including codon usage, posttranslational modification and inducible gene expression.