期刊
BIOORGANIC CHEMISTRY
卷 29, 期 5, 页码 308-320出版社
ACADEMIC PRESS INC
DOI: 10.1006/bioo.2001.1219
关键词
fluorescence; chemical sensor; boronic acid; molecular imprinting; polymerization; saccharides
资金
- NCI NIH HHS [CA88343] Funding Source: Medline
- NIDDK NIH HHS [DK55062] Funding Source: Medline
The ability to custom-make fluorescent sensors for different analytes could have a tremendous impact in a variety of areas. Template-directed polymerization or molecular imprinting seems to be a promising approach for the preparation of high-affinity and specific binding sites for different template molecules. However, the application of molecular imprinting in the preparation of fluorescent sensors has been hampered by the lack of suitable fluorescent tags, which would respond to the binding event with significant fluorescence intensity changes. We have designed and synthesized a fluorescent monomer (1) that allows for the preparation of fluorescent sensors of cis diols using molecular imprinting methods. This monomer has been used for the preparation of imprinted polymers as sensitive fluorescent sensors for D-fructose. The imprinted polymers prepared showed significant fluorescence intensity enhancement upon binding with the template carbohydrate. t (C) 2001 Academic Press.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据