4.2 Article

Common Genetic Variants Explain the Majority of the Correlation Between Height and Intelligence: The Generation Scotland Study

期刊

BEHAVIOR GENETICS
卷 44, 期 2, 页码 91-96

出版社

SPRINGER
DOI: 10.1007/s10519-014-9644-z

关键词

Height; Intelligence; Molecular genetics; Genetic correlation; Generation Scotland

资金

  1. Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6]
  2. Scottish Funding Council [HR03006]
  3. UK Medical Research Council (MRC)
  4. MRC
  5. Alzheimer Scotland
  6. BBSRC
  7. Chief Scientist Office [CZD/16/6/4] Funding Source: researchfish
  8. Medical Research Council [G0100266, MR/K026992/1] Funding Source: researchfish
  9. MRC [G0100266] Funding Source: UKRI

向作者/读者索取更多资源

Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.2
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据