Thermodynamic study of the solubility of some sulfonamides in octanol, water, and the mutually saturated solvents

The free energy, enthalpy and entropy of solution, were evaluated from solubility data fora group of sulfonamides from 25 to 40 degreesC in octanol, water, and the Mutually saturated solvents. In aqueous media, the solubility was determined at the isoelectric point and ionic strength 0.15 mol-L-1. The excess free energy and the activity coefficients of the solutes also were determined. The results are discussed in terms of solute-solvent interactions.