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Order out of complexity - protein structures that interact with heparin

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CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 11, 期 5, 页码 623-628

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CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-440X(00)00257-8

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  1. NHLBI NIH HHS [HL 52622] Funding Source: Medline

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Many proteins of widely differing functionality and structure are capable of binding heparin. Structural characterisations of the many types of such complexes are being reported in ever-increasing number and at improved resolution. Several crystal structures of complexes formed through the interaction of heparin-derived oligosaccharides with one or more protein partners have been described.

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