期刊
BRAIN INJURY
卷 15, 期 10, 页码 903-910出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/02699050110065709
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Primary objective: To determine if electrical stimulation (ES) benefits (waking time, 3-month outcomes) treated coma patients. Research design: Double blind randomized-controlled study. Methods and procedures: Ten coma patients; six treatment and four controls, using the 'Respond Select' by EMPI. Experimental interventions: Treatment group received radial nerve ES applied in 300 ms intermittent pulses at 40 Hz, 15-20 m Angstrom 8 hours a day up to 14 days of coma; control group received sham stimulation. Main outcomes and results: ES group emerged from coma mean 2 days earlier than controls, although this result was not statistically significant. At 3 months post-injury, there was no group difference in Glasgow Outcome Scale, although the ES group had improved function over controls as measured by the FIM/FAM (mean of 114 and 64.5, respectively, n.s.). Conclusions : These data show an interesting trend, although statistical power was limited in this small pilot study, suggesting the need for a larger trial.
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