期刊
CURRENT OPINION IN CHEMICAL BIOLOGY
卷 5, 期 5, 页码 584-590出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S1367-5931(00)00247-7
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资金
- NIGMS NIH HHS [GM 33225] Funding Source: Medline
Partial alignment of biomolecules in solution has added a new dimension to structural investigation by high-resolution NMR methods. Applications to proteins, nucleic acids and carbohydrates now abound. Limitations initially associated with compatibility of biomolecules with the liquid-crystal media commonly used to achieve alignment have begun to disappear. This is, in part, a result of the introduction of a wide variety of new media. Future applications to biologically important problems such as the structural organization of multi-domain proteins and multi-protein assemblies look very promising.
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