期刊
BIOTECHNOLOGY LETTERS
卷 23, 期 19, 页码 1551-1557出版社
KLUWER ACADEMIC PUBL
DOI: 10.1023/A:1011913225764
关键词
algorithm; identification; metabolic pathways; P-graph
A rigorous method for identifying biochemical reaction or metabolic pathways through its systematic synthesis has been established. The current method for synthesizing networks of metabolic pathways follows the general framework of a highly exacting combinatorial method. The method is capable of generating not only all combinatorially independent, feasible reaction networks only once, but also those combinations of independent pathways. A case study involving the conversion of glucose to pyruvate with 14 elementary reactions illustrates the efficiency and efficacy of the method. All the results have been obtained with a PC (Pentium-III 550 MHz, 256 MB RAM) within 1 s.
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