期刊
NATURE REVIEWS CANCER
卷 1, 期 1, 页码 46-54出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/35094059
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资金
- NCI NIH HHS [U01 CA143233-01, U54 CA143836, U54 CA112970-01, R01 CA064786-05, U54 CA126552, U54 CA143836-01, R01 CA057621-11, U54 CA112970, U54 CA126552-01, R01 CA057621, U01 CA143233, R01 CA064786] Funding Source: Medline
The interactions between cancer cells and their micro- and macroenvironment create a context that promotes tumour growth and protects it from immune attack. The functional association of cancer cells with their surrounding tissues forms a new 'organ' that changes as malignancy progresses. Investigation of this process might provide new insights into the mechanisms of tumorigenesis and could also lead to new therapeutic targets.
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