期刊
JOURNAL OF CLINICAL PERIODONTOLOGY
卷 28, 期 10, 页码 923-929出版社
WILEY
DOI: 10.1034/j.1600-051x.2001.028010923.x
关键词
infrabony defect; regeneration; enamel matrix proteins; radiographs
Objectives: The aim of this multicenter trial was to compare the clinical and radiographical outcome of a ready-to-use Emdogain((R))-gel (test) with the marketed Emdogain((R)) (control). Methods: Subjects with bilateral infrabony defects greater than or equal to4 mm deep and greater than or equal to2 mm wide according to radiographs were selected. 88 subjects with probing pocket depth (PPD) greater than or equal to6 mm greater than or equal to1 month after supervised oral hygiene and scaling participated. At baseline plaque index, bleeding on probing, PPD and probing attachment level were recorded and reproducible radiographs for computer-based bone level measurements were taken, In each subject, I tooth was randomly treated with the test and I tooth with the control gel. Examinations were repeated 8 and 16 months post-operatively. Results: After 16 months. the mean test PPD was 4.1 mm and the mean control PPD 4.2 mm. The mean gain of attachment was 2.7 mm for test and 2.9 mm for the control sites, and the radiographic measurements demonstrated a mean gain of 1 mm for both test and control sites. Conclusion: This series of cases demonstrated a statistically significant reduction of pocket depths and gain of attachment and bone after 8 and 16 months with no difference between the 2 preparations.
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