期刊
NATURE REVIEWS IMMUNOLOGY
卷 1, 期 1, 页码 41-49出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/35095564
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Natural killer cells are innate immune cells that control certain microbial infections and tumours. The function of natural killer cells is regulated by a balance between signals transmitted by activating receptors, which recognize ligands on tumours and virus-infected cells, and inhibitory receptors specific for major histocompatibility complex class I molecules. Here, we review the emerging evidence that natural killer cells have an important role in vivo in immune defence.
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