Adhesion signaling:: How β-catenin interacts with its partners

The multi-functional protein beta -catenin plays essential roles in cell-cell adhesion and nuclear signaling. Elucidation of the structures of beta -catenin complexes is beginning to clarify how beta -catenin uses the same surface to bind its various partners, and provides insights into how these interactions might be regulated. (C) 2001 Elsevier Science Ltd. All rights reserved.