期刊
TETRAHEDRON
卷 57, 期 41, 页码 8647-8651出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(01)00859-6
关键词
rhazinilam; alkylation; thiophenylimine; pyrrole
2-Piperidone has been converted into (+/-)-rhazinilam in nine steps in 8% overall yield. The key transformation involves the conversion of the lactam 5 into the annulated pyrrole derivative 3 via the thiophenyl imine 8. (C) 2001 Published by Elsevier Science Ltd.
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