期刊
AIDS
卷 15, 期 15, 页码 2043-2045出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00002030-200110190-00019
关键词
-
资金
- NIMH NIH HHS [R01 MH49981, R01 MH46618] Funding Source: Medline
The neuropeptide, substance P, is a potent modulator of neuroimmunoregulation. Substance P and its receptor modulate HIV infection. HIV-seropositive men had significantly higher plasma substance P levels compared with uninfected controls, which were associated with decreased CD16 and CD56 natural killer (NK) cell populations. The changes in plasma substance P levels and decreases in NK subsets did not correlate with CD4 cell levels, but a diurnal pattern was suggested for substance P. The balance between substance P expression and functions of immune cells may be important in the immunopathogenesis of HIV infection.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据