期刊
NEUROLOGY
卷 57, 期 8, 页码 1515-1517出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.57.8.1515
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The antioxidant N-acetylcysteine (NAG) or placebo was administered in a double-blind fashion to patients who met National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association criteria for probable AD. Testing for efficacy occurred after 3 and 6 months of treatment. Comparison of interval change favored NAC treatment on nearly every outcome measure, although significant differences were obtained only for a subset of cognitive tasks.
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